Nuytsland Nature Reserve is a protected area of Western Australia in the far south eastern part of the state.
Nominally located at 32° 18' S 125° 52' E, it has an area of 6,253.44 km², and takes in over 500 kilometers of coastline from Cape Pasley to Red Rocks Point. It was gazetted in 1969. Significant features include Twilight Cove and the Eyre Bird Observatory.